Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating-like protein; Belongs to the 3-beta-HSD family. (361 aa)    
Predicted Functional Partners:
MSMO1
C-4 methylsterol oxidase-like protein; Belongs to the sterol desaturase family.
   
 0.994
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 0.992
SQLE
Squalene epoxidase.
   
 
 0.988
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
 
 
 0.965
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
 
 
 0.964
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.955
FDFT1
Farnesyl-diphosphate farnesyltransferase 1.
  
 
 0.946
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.945
SC5D
Lathosterol oxidase-like protein; Belongs to the sterol desaturase family.
   
 0.935
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
 
 0.931
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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