STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUAK1NUAK family kinase 1. (667 aa)    
Predicted Functional Partners:
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
  
 
0.926
USP9X
Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family.
    
 
 0.647
ARHGAP28
Rho GTPase activating protein 28.
   
  
 0.586
NPAS4
Neuronal PAS domain protein 4.
      
 0.515
STMN1
Platelet-activating factor acetylhydrolase.
      
 0.489
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
      
 0.485
GSC
Goosecoid homeobox.
      
 0.478
DDRGK1
DDRGK domain containing 1.
      
 0.476
MPZL3
Myelin protein zero like 3.
      
 0.473
PLEKHA5
Pleckstrin homology domain containing A5.
      
 0.470
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.