Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
F6TWR4_HORSEUncharacterized protein. (142 aa)    
Predicted Functional Partners:
CDCA8
Cell division cycle associated 8.
   
 0.999
INCENP
Inner centromere protein.
   
 0.997
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.994
CASP9
Caspase 9; Belongs to the peptidase C14A family.
   
 0.989
XIAP
X-linked inhibitor of apoptosis.
    
 0.987
PLK1
Serine/threonine-protein kinase PLK.
   
 0.986
AURKA
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.986
DIABLO
Diablo IAP-binding mitochondrial protein.
    
 0.984
CASP3
Caspase-3-like protein; Belongs to the peptidase C14A family.
   
 0.981
CDCA3
Cell division cycle associated 3.
   
  
 0.979
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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