Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXO28F-box protein 28. (368 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
   
 
 0.961
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 
 0.894
RMND5A
Required for meiotic nuclear division 5 homolog A.
   
  
 0.807
IMPACT
Impact RWD domain protein.
   
  
 0.799
WDR37
WD repeat domain 37.
    
 
 0.719
SMTNL2
Smoothelin like 2.
   
  
 0.701
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
      
 0.689
ZNF483
Zinc finger protein 483.
      
 0.687
ZNHIT3
Zinc finger HIT-type containing 3.
      
 0.687
HRH4
Histamine receptor H4; Belongs to the G-protein coupled receptor 1 family.
      
 0.601
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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