STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)    
Predicted Functional Partners:
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
    
 0.833
LOC111774036
Histone H3; Belongs to the histone H3 family.
 
 
 0.824
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
    
 0.824
CENPA
Centromere protein A.
   
 0.803
HIST2H3C
Histone H3; Belongs to the histone H3 family.
 
 
 0.799
LOC100053259
Histone H3; Belongs to the histone H3 family.
 
 
 0.799
F7DCC3_HORSE
Histone H3; Belongs to the histone H3 family.
 
 
 0.798
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.796
H2AX
Histone H2A; Belongs to the histone H2A family.
 
 0.788
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.785
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.