Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
EPHA5EPH receptor A5. (1039 aa)    
Predicted Functional Partners:
EFNA5
Ephrin A5; Belongs to the ephrin family.
   
 0.905
EFNA1
Ephrin A1; Belongs to the ephrin family.
   
 0.874
EFNA3
Ephrin RBD domain-containing protein; Belongs to the ephrin family.
   
 0.857
EFNA4
Ephrin A4; Belongs to the ephrin family.
   
 0.851
EFNA2
Ephrin A2; Belongs to the ephrin family.
   
 0.851
EFNB2
Ephrin-B2; Belongs to the ephrin family.
   
 0.812
EFNB1
Ephrin B1; Belongs to the ephrin family.
   
 0.795
EFNB3
Ephrin B3; Belongs to the ephrin family.
   
 0.758
SH3BP5L
SH3 binding domain protein 5 like.
    
 
 0.702
RASA1
RAS p21 protein activator 1.
   
 0.611
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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