Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H1-1Histone cluster 1 H1 family member a. (267 aa)    
Predicted Functional Partners:
H2AC20
Histone H2A; Belongs to the histone H2A family.
   
 0.767
H1-8
H15 domain-containing protein.
   
 0.744
GRK3
G protein-coupled receptor kinase 3.
      
 0.683
ENSA
Endosulfine alpha; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.
   
  
 0.636
GRK3-2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
      
 0.621
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.
      
 0.578
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.544
AKAP8
A-kinase anchoring protein 8; Belongs to the AKAP95 family.
      
 0.528
DPP9
Dipeptidyl peptidase 9; Belongs to the peptidase S9B family.
      
 0.525
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.506
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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