Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
F6W876_HORSEZnF_CDGSH domain-containing protein. (106 aa)    
Predicted Functional Partners:
CISD3
CDGSH iron sulfur domain 3.
   
  
 0.592
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 
 0.470
CARS1
Cysteinyl-tRNA synthetase.
      
 0.448
CARS2
Cysteinyl-tRNA synthetase 2, mitochondrial.
      
 0.441
DDB1
Damage specific DNA binding protein 1.
    
 
 0.432
HSBP1
Heat shock factor binding protein 1.
      
 0.431
MIEN1
Migration and invasion enhancer 1.
   
  
 0.401
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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