Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (377 aa)    
Predicted Functional Partners:
PTGR1
Prostaglandin reductase 1.
  
 0.914
PTGR2
Uncharacterized protein.
  
 0.914
HPGD
15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.895
LTA4H
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
     
 0.890
DTYMK
Deoxythymidylate kinase.
      
 0.829
CRYZL1
Crystallin zeta like 1.
  
   
 0.807
XYLB
Xylulokinase.
  
 
 0.747
MECR
Mitochondrial trans-2-enoyl-CoA reductase.
   
  
 0.670
ZNF407
Zinc finger protein 407.
    
 0.644
PEX5
Peroxisomal biogenesis factor 5.
   
 
 0.639
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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