STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INKA2Inka box actin regulator 2. (292 aa)    
Predicted Functional Partners:
CLMP
CXADR like membrane protein.
      
 0.769
CLMP-2
Ig-like domain-containing protein.
      
 0.769
PRTG
Protogenin.
    
 
 0.687
ESRP2
Epithelial splicing regulatory protein 2.
   
  
 0.672
KCNIP3
Uncharacterized protein.
      
 0.664
PAK4
Non-specific serine/threonine protein kinase.
   
  
 0.655
PROS1
Protein S.
      
 0.625
TP53INP1
Tumor protein p53 inducible nuclear protein 1.
   
  
 0.540
LZTS2
Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin.
      
 0.519
BUD13
BUD13 homolog.
      
 0.487
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.