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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (241 aa)    
Predicted Functional Partners:
TOPBP1
DNA topoisomerase II binding protein 1.
   
 0.952
CLSPN
Claspin.
   
 
 0.942
RAD1
RAD1 checkpoint DNA exonuclease.
   
 0.909
HUS1
Checkpoint protein; Belongs to the HUS1 family.
   
 0.890
SLF1
SMC5-SMC6 complex localization factor 1.
   
 0.870
WRN
WRN RecQ like helicase.
     
 0.855
RAD9A
Cell cycle checkpoint control protein; Belongs to the rad9 family.
   
 0.837
ATRIP
ATR interacting protein.
   
 
 0.816
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
      
 0.761
PWP1
PWP1 homolog, endonuclein.
   
  
 0.759
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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