Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C2Complement C2; Belongs to the peptidase S1 family. (704 aa)    
Predicted Functional Partners:
LOC100059239
Uncharacterized protein.
   
 0.954
C1R
Complement C1r; Belongs to the peptidase S1 family.
   
 0.946
MASP1
Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
   
 0.921
C1QB
Complement C1q B chain.
   
 0.914
LOC100066313
C-type lectin domain-containing protein.
   
 0.911
C1S
Complement C1s; Belongs to the peptidase S1 family.
   
 0.910
MASP2
Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
   
 0.908
MBL2
Mannose binding lectin 2.
    
 0.907
C1QC
Complement C1q C chain.
   
 0.906
LOC100060505
Uncharacterized protein.
   
 0.894
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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