STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRN4CLLRRN4 C-terminal like. (236 aa)    
Predicted Functional Partners:
SAPCD2
Suppressor APC domain containing 2.
      
 0.594
PDCL2
Phosducin like 2.
      
 0.579
IGSF9B
Immunoglobulin superfamily member 9B.
   
  
 0.576
TMEM45B
Transmembrane protein 45B.
   
  
 0.576
SLC44A4
Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family.
   
  
 0.568
TMPRSS11A
Transmembrane protease serine; Belongs to the peptidase S1 family.
      
 0.567
TLCD4
TLCD4-RWDD3 readthrough.
   
  
 0.561
CACNG4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
  
 0.520
PREX2
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2.
   
  
 0.511
NGEF
Neuronal guanine nucleotide exchange factor.
      
 0.495
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.