DUSP4 protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DUSP4

Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (411 aa)

Predicted Functional Partners:

MAPK3

0.951

MAPK1

0.951

MAPK10

0.857

MAPK8

0.840

MAPK9

0.812

MAPK11

0.799

MAPK14

0.799

MAPK12

0.793

MAPK13

0.793

SPRY4

0.558

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP4	MAPK1	ENSECAP00000003752	ENSECAP00000048276	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.951
DUSP4	MAPK10	ENSECAP00000003752	ENSECAP00000048978	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.857
DUSP4	MAPK11	ENSECAP00000003752	ENSECAP00000004442	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.799
DUSP4	MAPK12	ENSECAP00000003752	ENSECAP00000015310	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.793
DUSP4	MAPK13	ENSECAP00000003752	ENSECAP00000041374	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.793
DUSP4	MAPK14	ENSECAP00000003752	ENSECAP00000012557	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.799
DUSP4	MAPK3	ENSECAP00000003752	ENSECAP00000012473	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.951
DUSP4	MAPK8	ENSECAP00000003752	ENSECAP00000006681	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.840
DUSP4	MAPK9	ENSECAP00000003752	ENSECAP00000034682	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.812
DUSP4	SPRY4	ENSECAP00000003752	ENSECAP00000003701	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Sprouty RTK signaling antagonist 4.	0.558
MAPK1	DUSP4	ENSECAP00000048276	ENSECAP00000003752	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.951
MAPK1	MAPK11	ENSECAP00000048276	ENSECAP00000004442	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.950
MAPK1	MAPK12	ENSECAP00000048276	ENSECAP00000015310	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.935
MAPK1	MAPK13	ENSECAP00000048276	ENSECAP00000041374	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.937
MAPK1	MAPK14	ENSECAP00000048276	ENSECAP00000012557	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.951
MAPK1	MAPK3	ENSECAP00000048276	ENSECAP00000012473	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.989
MAPK1	MAPK9	ENSECAP00000048276	ENSECAP00000034682	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase.	0.406
MAPK10	DUSP4	ENSECAP00000048978	ENSECAP00000003752	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.857
MAPK10	MAPK11	ENSECAP00000048978	ENSECAP00000004442	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.931
MAPK10	MAPK12	ENSECAP00000048978	ENSECAP00000015310	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.928

page 1 of 5

Server load: low (26%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About