STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3GLB2SH3 domain containing GRB2 like, endophilin B2. (537 aa)    
Predicted Functional Partners:
WDR45B
WD repeat domain 45B.
   
  
 0.688
SH3GLB1
SH3 domain containing GRB2 like, endophilin B1.
  
 
 
0.642
DYNC1I2
Dynein cytoplasmic 1 intermediate chain 2.
      
 0.588
SHANK1
SH3 and multiple ankyrin repeat domains 1.
    
  0.577
SHANK3
SH3 and multiple ankyrin repeat domains 3.
    
  0.577
ATG4D
Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.
   
  
 0.559
USP14
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
   0.499
ARHGAP4
Rho GTPase activating protein 4.
   
  
 0.494
DPYSL3
Dihydropyrimidinase like 3.
      
 0.489
BECN2
Beclin 2.
    
 
 0.485
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.