STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PMCHPro-melanin concentrating hormone. (151 aa)    
Predicted Functional Partners:
MCHR2
Melanin concentrating hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.991
MCHR1
Melanin concentrating hormone receptor 1.
   
 
 0.989
HCRT
Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family.
   
 
 0.964
PNOC
Prepronociceptin.
     
 0.750
PDYN
Prodynorphin.
   
 
 0.741
QRFP
Pyroglutamylated RFamide peptide.
  
  
 0.734
POMC
Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family.
     
 0.722
AGRP
Agouti related neuropeptide.
      
 0.713
OXT
Oxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family.
   
 
 0.703
GAL
Galanin and GMAP prepropeptide.
     
 0.690
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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