STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO45F-box protein 45. (285 aa)    
Predicted Functional Partners:
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.965
SPRYD3
SPRY domain containing 3.
   
 
 0.936
KCTD6
Potassium channel tetramerization domain containing 6.
     
 0.914
MYCBP2
MYC binding protein 2.
    
 
 0.909
CIT
Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
      
 0.772
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.758
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.724
ELOC
Elongin C; Belongs to the SKP1 family.
   
 0.683
FBXL14
F-box and leucine rich repeat protein 14.
   
 
 0.637
MRPL3
Mitochondrial ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
 
 
    0.625
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.