STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPTC7Protein phosphatase; Belongs to the PP2C family. (308 aa)    
Predicted Functional Partners:
FAM216A
Family with sequence similarity 216 member A.
      
 0.794
GPN3
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
   
  
 0.780
HVCN1
Hydrogen voltage gated channel 1.
      
 0.763
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
 
 
  
 0.759
TCTN1
Tectonic family member 1.
      
 0.744
CCDC63
Coiled-coil domain containing 63.
   
 
 0.724
ANAPC7
Anaphase promoting complex subunit 7.
   
  
 0.695
SSRP1
HMG box domain-containing protein.
   
 
 0.695
RAD9B
Cell cycle checkpoint control protein; Belongs to the rad9 family.
      
 0.676
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
   
 
 0.612
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.