STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HENMT1HEN methyltransferase 1. (422 aa)    
Predicted Functional Partners:
MOV10L1
Mov10 like RISC complex RNA helicase 1.
     
 0.920
GTSF1
Gametocyte specific factor 1.
      
 0.902
PIWIL3
Piwi like RNA-mediated gene silencing 3; Belongs to the argonaute family.
   
 0.895
DDX39A
DExD-box helicase 39A.
    
 0.858
PNLDC1
PARN like, ribonuclease domain containing 1.
      
 0.855
FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6; Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be re [...]
      
 0.812
SPEM1
Spermatid maturation 1.
   
  
 0.785
SGSM1
Small G protein signaling modulator 1.
      
 0.671
F6UIV7_HORSE
Uncharacterized protein.
      
 0.634
ZGLP1
GATA-type domain-containing protein.
      
 0.634
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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