STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100A2S100 calcium binding protein A2. (223 aa)    
Predicted Functional Partners:
S100A13
S100 calcium binding protein A13; Belongs to the S-100 family.
   
  
 0.641
S100G
Protein S100-G; Belongs to the S-100 family.
      
 0.623
S100A1
Protein S100; Belongs to the S-100 family.
   
 
0.588
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
    
 0.566
WDR38
WD repeat domain 38.
   
 0.529
S100A14
S100 calcium binding protein A14; Belongs to the S-100 family.
   
 
 0.503
S100B
Protein S100; Belongs to the S-100 family.
   
0.492
SORBS3
Sorbin and SH3 domain containing 3.
    
 0.490
KNOP1
Lysine rich nucleolar protein 1.
      
 0.482
ADIRF
Adipogenesis regulatory factor.
      
 0.477
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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