SH2B3 protein (Equus caballus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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Score

SH2B3

SH2B adaptor protein 3. (561 aa)

Predicted Functional Partners:

SH2B1

0.920

NTRK1

0.920

NTRK2

0.919

JAK2

0.775

SPATA9

0.742

KITLG

0.687

SETBP1

0.678

TOX2

0.636

ARHGEF3

0.635

CBL

0.618

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF3	SH2B3	ENSECAP00000013073	ENSECAP00000005095	Rho guanine nucleotide exchange factor 3.	SH2B adaptor protein 3.	0.635
ARHGEF3	TOX2	ENSECAP00000013073	ENSECAP00000054897	Rho guanine nucleotide exchange factor 3.	TOX high mobility group box family member 2.	0.747
CBL	JAK2	ENSECAP00000003427	ENSECAP00000008048	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.597
CBL	KITLG	ENSECAP00000003427	ENSECAP00000000163	Cbl proto-oncogene.	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	0.493
CBL	SH2B1	ENSECAP00000003427	ENSECAP00000021111	Cbl proto-oncogene.	SH2B adaptor protein 1.	0.654
CBL	SH2B3	ENSECAP00000003427	ENSECAP00000005095	Cbl proto-oncogene.	SH2B adaptor protein 3.	0.618
JAK2	CBL	ENSECAP00000008048	ENSECAP00000003427	Tyrosine-protein kinase.	Cbl proto-oncogene.	0.597
JAK2	KITLG	ENSECAP00000008048	ENSECAP00000000163	Tyrosine-protein kinase.	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	0.553
JAK2	SETBP1	ENSECAP00000008048	ENSECAP00000029051	Tyrosine-protein kinase.	SET binding protein 1.	0.468
JAK2	SH2B1	ENSECAP00000008048	ENSECAP00000021111	Tyrosine-protein kinase.	SH2B adaptor protein 1.	0.886
JAK2	SH2B3	ENSECAP00000008048	ENSECAP00000005095	Tyrosine-protein kinase.	SH2B adaptor protein 3.	0.775
KITLG	CBL	ENSECAP00000000163	ENSECAP00000003427	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	Cbl proto-oncogene.	0.493
KITLG	JAK2	ENSECAP00000000163	ENSECAP00000008048	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	Tyrosine-protein kinase.	0.553
KITLG	NTRK1	ENSECAP00000000163	ENSECAP00000034311	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	Tyrosine-protein kinase receptor.	0.743
KITLG	NTRK2	ENSECAP00000000163	ENSECAP00000030735	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	Tyrosine-protein kinase receptor.	0.743
KITLG	SH2B3	ENSECAP00000000163	ENSECAP00000005095	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	SH2B adaptor protein 3.	0.687
NTRK1	KITLG	ENSECAP00000034311	ENSECAP00000000163	Tyrosine-protein kinase receptor.	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	0.743
NTRK1	SH2B1	ENSECAP00000034311	ENSECAP00000021111	Tyrosine-protein kinase receptor.	SH2B adaptor protein 1.	0.924
NTRK1	SH2B3	ENSECAP00000034311	ENSECAP00000005095	Tyrosine-protein kinase receptor.	SH2B adaptor protein 3.	0.920
NTRK2	KITLG	ENSECAP00000030735	ENSECAP00000000163	Tyrosine-protein kinase receptor.	Processed kit ligand; Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins (By similarity); Belongs to the SCF family.	0.743