STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1967 aa)    
Predicted Functional Partners:
CXXC1
CXXC finger protein 1.
   
 0.972
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.970
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.970
WDR82
WD repeat domain 82.
   
 0.968
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 0.943
WDR5
WD repeat domain 5.
   
 0.939
SETD1A
SET domain containing 1A, histone lysine methyltransferase.
   
 
0.808
KMT2D
Lysine methyltransferase 2D.
   
0.800
KMT2A
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
   
0.731
KMT2B
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
   
0.731
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.