FN1 protein (Equus caballus) - STRING interaction network

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FN1

Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). (2477 aa)

Predicted Functional Partners:

ITGB3

0.963

ITGB1

0.952

ITGB7

0.951

SDC4

0.944

ITGB6

0.943

ITGB5

0.942

ITGB8

0.940

ITGA8

0.927

ITGA2B

0.927

ITGAV

0.927

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FN1	ITGA2B	ENSECAP00000005223	ENSECAP00000018357	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	0.927
FN1	ITGA8	ENSECAP00000005223	ENSECAP00000011756	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	0.927
FN1	ITGAV	ENSECAP00000005223	ENSECAP00000042187	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Family with sequence similarity 171 member B; Belongs to the integrin alpha chain family.	0.927
FN1	ITGB1	ENSECAP00000005223	ENSECAP00000046507	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.952
FN1	ITGB3	ENSECAP00000005223	ENSECAP00000016485	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.963
FN1	ITGB5	ENSECAP00000005223	ENSECAP00000035882	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.942
FN1	ITGB6	ENSECAP00000005223	ENSECAP00000019961	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.943
FN1	ITGB7	ENSECAP00000005223	ENSECAP00000011576	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.951
FN1	ITGB8	ENSECAP00000005223	ENSECAP00000016855	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.940
FN1	SDC4	ENSECAP00000005223	ENSECAP00000025392	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.944
ITGA2B	FN1	ENSECAP00000018357	ENSECAP00000005223	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	0.927
ITGA2B	ITGAV	ENSECAP00000018357	ENSECAP00000042187	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	Family with sequence similarity 171 member B; Belongs to the integrin alpha chain family.	0.942
ITGA2B	ITGB1	ENSECAP00000018357	ENSECAP00000046507	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.928
ITGA2B	ITGB3	ENSECAP00000018357	ENSECAP00000016485	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGA2B	ITGB5	ENSECAP00000018357	ENSECAP00000035882	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.811
ITGA2B	ITGB6	ENSECAP00000018357	ENSECAP00000019961	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.837
ITGA2B	ITGB7	ENSECAP00000018357	ENSECAP00000011576	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.761
ITGA2B	ITGB8	ENSECAP00000018357	ENSECAP00000016855	Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.807
ITGA8	FN1	ENSECAP00000011756	ENSECAP00000005223	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	0.927
ITGA8	ITGAV	ENSECAP00000011756	ENSECAP00000042187	Integrin subunit alpha 8; Belongs to the integrin alpha chain family.	Family with sequence similarity 171 member B; Belongs to the integrin alpha chain family.	0.686

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