STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEC63SEC63 homolog, protein translocation regulator. (760 aa)    
Predicted Functional Partners:
SEC62
SEC62 homolog, preprotein translocation factor.
   
 0.999
SEC61B
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 
 0.992
SEC61A2
SEC61 translocon alpha 2 subunit.
   
 
 0.990
SEC61A1
SEC61 translocon alpha 1 subunit.
   
 
 0.990
SEC61G
SEC61 translocon gamma subunit.
   
 
 0.985
HSPA5
Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family.
  
 
 0.885
ANKRD45
Ankyrin repeat domain 45.
  
 
 0.881
SPCS1
Signal peptidase complex subunit 1.
   
 
 0.833
HYOU1
Hypoxia up-regulated 1.
  
 
 0.763
SRP54
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.
   
  
 0.763
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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