STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (880 aa)    
Predicted Functional Partners:
HCN3
Hyperpolarization activated cyclic nucleotide gated potassium channel 3.
  
 
0.939
ASTN1
Astrotactin 1.
      
 0.820
AP3B2
Adaptor related protein complex 3 subunit beta 2.
   
  
 0.772
PTPRT
Protein tyrosine phosphatase receptor type T.
   
  
 0.741
KLHL14
Kelch like family member 14.
      
 0.670
SP8
Sp8 transcription factor.
   
  
 0.651
SEMA3E
Semaphorin 3E; Belongs to the semaphorin family.
      
 0.635
HCN2
Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2.
  
  
 
0.549
STX1A
Syntaxin 1A; Belongs to the syntaxin family.
   
 
 0.546
HCN4
Hyperpolarization activated cyclic nucleotide gated potassium channel 4.
  
  
 
0.544
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.