STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FXR2FMR1 autosomal homolog 2. (673 aa)    
Predicted Functional Partners:
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
   
 0.980
FXR1
FMR1 autosomal homolog 1.
  
 
0.979
FMR1
Fragile X mental retardation 1.
  
 
0.972
CPEB4
Cytoplasmic polyadenylation element binding protein 4.
    
 
 0.903
CPEB3
Cytoplasmic polyadenylation element binding protein 3.
    
 
 0.895
CPEB2
Cytoplasmic polyadenylation element binding protein 2.
    
 
 0.877
PUF60
Poly(U) binding splicing factor 60.
      
 0.856
G3BP2
G3BP stress granule assembly factor 2.
   
 
 0.845
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 
 0.807
G3BP1
G3BP stress granule assembly factor 1.
    
 
 0.778
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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