GET1 protein (Equus caballus) - STRING interaction network

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Score

GET1

Guided entry of tail-anchored proteins factor 1. (174 aa)

Predicted Functional Partners:

GET3

0.989

CAMLG

0.959

SETD4

0.799

MORC3

0.740

SPO11

0.692

SH3BGR

0.683

DYRK1A

0.660

SEC61B

0.608

SGTA

0.578

TBATA

0.567

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAMLG	GET1	ENSECAP00000001243	ENSECAP00000005864	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Guided entry of tail-anchored proteins factor 1.	0.959
CAMLG	GET3	ENSECAP00000001243	ENSECAP00000005353	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.958
CAMLG	SGTA	ENSECAP00000001243	ENSECAP00000008248	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Small glutamine rich tetratricopeptide repeat containing alpha.	0.720
DYRK1A	GET1	ENSECAP00000044624	ENSECAP00000005864	Dual specificity tyrosine phosphorylation regulated kinase 1A.	Guided entry of tail-anchored proteins factor 1.	0.660
GET1	CAMLG	ENSECAP00000005864	ENSECAP00000001243	Guided entry of tail-anchored proteins factor 1.	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	0.959
GET1	DYRK1A	ENSECAP00000005864	ENSECAP00000044624	Guided entry of tail-anchored proteins factor 1.	Dual specificity tyrosine phosphorylation regulated kinase 1A.	0.660
GET1	GET3	ENSECAP00000005864	ENSECAP00000005353	Guided entry of tail-anchored proteins factor 1.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.989
GET1	MORC3	ENSECAP00000005864	ENSECAP00000032475	Guided entry of tail-anchored proteins factor 1.	MORC family CW-type zinc finger 3.	0.740
GET1	SEC61B	ENSECAP00000005864	ENSECAP00000022815	Guided entry of tail-anchored proteins factor 1.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.608
GET1	SETD4	ENSECAP00000005864	ENSECAP00000045356	Guided entry of tail-anchored proteins factor 1.	SET domain containing 4.	0.799
GET1	SGTA	ENSECAP00000005864	ENSECAP00000008248	Guided entry of tail-anchored proteins factor 1.	Small glutamine rich tetratricopeptide repeat containing alpha.	0.578
GET1	SH3BGR	ENSECAP00000005864	ENSECAP00000008599	Guided entry of tail-anchored proteins factor 1.	Uncharacterized protein.	0.683
GET1	SPO11	ENSECAP00000005864	ENSECAP00000010940	Guided entry of tail-anchored proteins factor 1.	SPO11 initiator of meiotic double stranded breaks.	0.692
GET1	TBATA	ENSECAP00000005864	ENSECAP00000012388	Guided entry of tail-anchored proteins factor 1.	Thymus, brain and testes associated.	0.567
GET3	CAMLG	ENSECAP00000005353	ENSECAP00000001243	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	0.958
GET3	GET1	ENSECAP00000005353	ENSECAP00000005864	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Guided entry of tail-anchored proteins factor 1.	0.989
GET3	SEC61B	ENSECAP00000005353	ENSECAP00000022815	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.680
GET3	SGTA	ENSECAP00000005353	ENSECAP00000008248	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	Small glutamine rich tetratricopeptide repeat containing alpha.	0.805
MORC3	GET1	ENSECAP00000032475	ENSECAP00000005864	MORC family CW-type zinc finger 3.	Guided entry of tail-anchored proteins factor 1.	0.740
MORC3	SETD4	ENSECAP00000032475	ENSECAP00000045356	MORC family CW-type zinc finger 3.	SET domain containing 4.	0.499