F6WB66_HORSE protein (Equus caballus) - STRING interaction network

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F6WB66_HORSE

Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (249 aa)

Predicted Functional Partners:

ASPN

0.580

TFPI2

0.556

SPI2

0.527

ENSECAP00000029318

0.511

ENSECAP00000044534

0.509

ALB

0.500

KLK12

0.499

MET

0.496

LGB1

0.479

KLK13

0.478

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	F6WB66_HORSE	ENSECAP00000041304	ENSECAP00000006501	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.500
ALB	LGB1	ENSECAP00000041304	ENSECAP00000007932	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Beta-lactoglobulin-1; Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule.	0.999
ALB	SPI2	ENSECAP00000041304	ENSECAP00000053574	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Alpha-1-antiproteinase 2; Inhibitor of serine proteases.	0.776
ASPN	F6WB66_HORSE	ENSECAP00000005362	ENSECAP00000006501	Asporin.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.580
ENSECAP00000029318	F6WB66_HORSE	ENSECAP00000029318	ENSECAP00000006501	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.511
ENSECAP00000029318	MET	ENSECAP00000029318	ENSECAP00000008993	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.496
ENSECAP00000044534	F6WB66_HORSE	ENSECAP00000044534	ENSECAP00000006501	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.509
ENSECAP00000044534	MET	ENSECAP00000044534	ENSECAP00000008993	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.496
F6WB66_HORSE	ALB	ENSECAP00000006501	ENSECAP00000041304	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.500
F6WB66_HORSE	ASPN	ENSECAP00000006501	ENSECAP00000005362	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Asporin.	0.580
F6WB66_HORSE	ENSECAP00000029318	ENSECAP00000006501	ENSECAP00000029318	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.511
F6WB66_HORSE	ENSECAP00000044534	ENSECAP00000006501	ENSECAP00000044534	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.509
F6WB66_HORSE	KLK12	ENSECAP00000006501	ENSECAP00000025569	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.499
F6WB66_HORSE	KLK13	ENSECAP00000006501	ENSECAP00000011741	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Kallikrein related peptidase 13; Belongs to the peptidase S1 family.	0.478
F6WB66_HORSE	LGB1	ENSECAP00000006501	ENSECAP00000007932	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Beta-lactoglobulin-1; Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule.	0.479
F6WB66_HORSE	MET	ENSECAP00000006501	ENSECAP00000008993	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.496
F6WB66_HORSE	SPI2	ENSECAP00000006501	ENSECAP00000053574	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Alpha-1-antiproteinase 2; Inhibitor of serine proteases.	0.527
F6WB66_HORSE	TFPI2	ENSECAP00000006501	ENSECAP00000016920	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Tissue factor pathway inhibitor.	0.556
KLK12	F6WB66_HORSE	ENSECAP00000025569	ENSECAP00000006501	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.499
KLK12	MET	ENSECAP00000025569	ENSECAP00000008993	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.496