STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CGRRF1Cell growth regulator with ring finger domain 1. (333 aa)    
Predicted Functional Partners:
RNF170
Ring finger protein 170.
   
  
 0.834
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
      
 0.689
RNF185
Ring finger protein 185.
      
 0.665
UBE2J1
Ubiquitin conjugating enzyme E2 J1.
    
 0.601
UBE2J2
Ubiquitin conjugating enzyme E2 J2.
   
  
 0.574
MARCHF6
Membrane associated ring-CH-type finger 6.
   
  
 0.563
CDKN3
Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
 
 
  
 0.562
UBE2G2
Ubiquitin conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.
      
 0.556
RNF13
Ring finger protein 13.
   
 
 0.552
ZNRF4
RING-type domain-containing protein.
    
 
 0.550
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.