STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORMDL2ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
   
 0.860
SPTSSA
Serine palmitoyltransferase small subunit A.
    
 0.854
SPTLC2
Serine palmitoyltransferase long chain base subunit 2.
    
 0.847
SPTLC3
Serine palmitoyltransferase long chain base subunit 3.
    
 0.776
SARNP
SAP domain containing ribonucleoprotein.
   
  
 0.698
GMPR
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
      
 0.653
SPTSSB
Serine palmitoyltransferase small subunit B.
     
 0.632
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma.
   
  
 0.619
GOLGA7
Golgin A7.
   
 
 0.574
ORMDL1
ORM1-like protein; Negative regulator of sphingolipid synthesis.
  
 
 
0.564
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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