STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE6CPhosphodiesterase. (854 aa)    
Predicted Functional Partners:
GNAT2
G protein subunit alpha transducin 2.
   
 0.930
PDE6H
Phosphodiesterase 6H.
   
 
 0.921
GMPR
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
    
 0.908
HPRT1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
GMPS
Guanine monophosphate synthase.
     
  0.900
CNGB3
Cyclic nucleotide gated channel subunit beta 3.
   
 0.869
CNGA3
Cyclic nucleotide gated channel subunit alpha 3.
   
 0.837
GUCY2D
Guanylate cyclase.
   
 0.820
EYS
Eyes shut homolog.
   
 
 0.797
GUCY2F
Guanylate cyclase.
   
 0.795
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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