STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1318 aa)    
Predicted Functional Partners:
CACNA2D3
Calcium voltage-gated channel auxiliary subunit alpha2delta 3.
    
 
 0.606
STRN4
Striatin 4.
   
 
 0.569
ASCC2
Activating signal cointegrator 1 complex subunit 2.
   
  
 0.558
IRF2BP2
Interferon regulatory factor 2 binding protein 2.
   
  
 0.534
VTN
Vitronectin.
      
 0.533
RAPGEF6
Uncharacterized protein.
   
 
 0.522
LINGO2
Uncharacterized protein.
      
 0.516
NFKBIE
NFKB inhibitor epsilon.
   
 0.508
RASA2
RAS p21 protein activator 2.
   
  
 0.492
PALM2AKAP2
PALM2-AKAP2 fusion.
      
 0.483
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.