TEAD1 protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TEAD1

TEA domain transcription factor 1. (437 aa)

Predicted Functional Partners:

YAP1

0.998

WWTR1

0.982

VGLL4

0.922

LATS1

0.913

TEAD2

0.905

TEAD4

0.903

TCF7L2

0.863

LEF1

0.815

TCF7L1

0.810

LATS2

0.797

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LATS1	LATS2	ENSECAP00000000899	ENSECAP00000028935	Large tumor suppressor kinase 1.	Non-specific serine/threonine protein kinase.	0.978
LATS1	TEAD1	ENSECAP00000000899	ENSECAP00000007014	Large tumor suppressor kinase 1.	TEA domain transcription factor 1.	0.913
LATS1	TEAD2	ENSECAP00000000899	ENSECAP00000015875	Large tumor suppressor kinase 1.	TEA domain transcription factor 2.	0.633
LATS1	TEAD4	ENSECAP00000000899	ENSECAP00000009776	Large tumor suppressor kinase 1.	Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.	0.737
LATS1	VGLL4	ENSECAP00000000899	ENSECAP00000024052	Large tumor suppressor kinase 1.	Vestigial like family member 4.	0.593
LATS1	WWTR1	ENSECAP00000000899	ENSECAP00000040179	Large tumor suppressor kinase 1.	WW domain containing transcription regulator 1.	0.989
LATS1	YAP1	ENSECAP00000000899	ENSECAP00000006765	Large tumor suppressor kinase 1.	Yes associated protein 1.	0.995
LATS2	LATS1	ENSECAP00000028935	ENSECAP00000000899	Non-specific serine/threonine protein kinase.	Large tumor suppressor kinase 1.	0.978
LATS2	TEAD1	ENSECAP00000028935	ENSECAP00000007014	Non-specific serine/threonine protein kinase.	TEA domain transcription factor 1.	0.797
LATS2	TEAD2	ENSECAP00000028935	ENSECAP00000015875	Non-specific serine/threonine protein kinase.	TEA domain transcription factor 2.	0.587
LATS2	TEAD4	ENSECAP00000028935	ENSECAP00000009776	Non-specific serine/threonine protein kinase.	Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.	0.773
LATS2	WWTR1	ENSECAP00000028935	ENSECAP00000040179	Non-specific serine/threonine protein kinase.	WW domain containing transcription regulator 1.	0.988
LATS2	YAP1	ENSECAP00000028935	ENSECAP00000006765	Non-specific serine/threonine protein kinase.	Yes associated protein 1.	0.995
LEF1	TCF7L1	ENSECAP00000038219	ENSECAP00000034125	Lymphoid enhancer binding factor 1.	Transcription factor 7 like 1.	0.952
LEF1	TCF7L2	ENSECAP00000038219	ENSECAP00000024463	Lymphoid enhancer binding factor 1.	Transcription factor 7 like 2.	0.982
LEF1	TEAD1	ENSECAP00000038219	ENSECAP00000007014	Lymphoid enhancer binding factor 1.	TEA domain transcription factor 1.	0.815
LEF1	TEAD2	ENSECAP00000038219	ENSECAP00000015875	Lymphoid enhancer binding factor 1.	TEA domain transcription factor 2.	0.823
LEF1	TEAD4	ENSECAP00000038219	ENSECAP00000009776	Lymphoid enhancer binding factor 1.	Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.	0.817
LEF1	YAP1	ENSECAP00000038219	ENSECAP00000006765	Lymphoid enhancer binding factor 1.	Yes associated protein 1.	0.842
TCF7L1	LEF1	ENSECAP00000034125	ENSECAP00000038219	Transcription factor 7 like 1.	Lymphoid enhancer binding factor 1.	0.952