Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C13H16orf72Chromosome 13 C16orf72 homolog. (279 aa)    
Predicted Functional Partners:
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
 
 0.810
F6XTK8_HORSE
CBFD_NFYB_HMF domain-containing protein.
    
 
 0.710
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
    
 
 0.664
RNASEH2C
Ribonuclease H2 subunit C.
    
 
 0.615
PHGDH
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
   0.607
IPO4
Importin 4.
    
   0.607
PLS3
Plastin 3.
    
   0.607
MARS1
Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
    
   0.578
RNASEH2B
Ribonuclease H2 subunit B.
      
 0.543
RNASEH2A
Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
      
 0.541
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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