STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)    
Predicted Functional Partners:
MAP2K7
Mitogen-activated protein kinase kinase 7.
    
0.926
TMEM41A
Transmembrane protein 41A.
      
 0.608
MYCBP2
MYC binding protein 2.
    
 
 0.528
SS18L1
SS18L1 subunit of BAF chromatin remodeling complex.
   
  
 0.484
OSBPL2
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.479
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
      
 0.478
PTPN4
Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton.
      
 0.472
KCNJ14
Potassium voltage-gated channel subfamily J member 14.
      
 0.470
RREB1
Ras responsive element binding protein 1.
      
 0.461
DSG4
Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
      
 0.443
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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