STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6XS64_HORSEPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (198 aa)    
Predicted Functional Partners:
RET-2
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
    0.532
KLK12
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
     0.522
LOC106782834
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
     0.521
LOC100050711
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
   
0.518
LOC100052229
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
   
0.513
LOC111768996
Peptidase S1 domain-containing protein.
  
   
0.509
F7
Coagulation factor VII.
  
     0.507
PRSS48
Serine protease 48; Belongs to the peptidase S1 family.
  
     0.505
LOC100055651
Peptidase S1 domain-containing protein.
   
   
0.499
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
   
  0.497
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (22%) [HD]