STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (312 aa)    
Predicted Functional Partners:
CDC25B
Cell division cycle 25B.
    
 0.980
WWTR1
WW domain containing transcription regulator 1.
    
 0.977
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.976
CDC25C
Cell division cycle 25C.
   
 0.971
YAP1
Yes associated protein 1.
   
 0.969
ARAF
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.956
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
   
 0.956
FOXO3
Forkhead box O3.
    
 0.950
BAD
BCL2 associated agonist of cell death.
   
 0.943
CTNNA1
Catenin alpha 1.
   
 
 0.925
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.