STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (213 aa)    
Predicted Functional Partners:
SLC22A11
Solute carrier family 22 member 11.
      
 0.840
KCNG1
Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family.
      
 0.827
FTCD
Formimidoyltransferase cyclodeaminase.
      
 0.795
RAB9B
RAB9B, member RAS oncogene family.
      
 0.671
ESR1
Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]
   
 
 0.641
BNIP3L
BCL2 interacting protein 3 like.
      
 0.628
LSP1
Lymphocyte specific protein 1.
      
 0.576
OPRK1
Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.570
HEXA
Beta-hexosaminidase.
      
 0.565
KCNH2
Potassium voltage-gated channel subfamily H member 2.
      
 0.549
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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