STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMEMembrane metalloendopeptidase. (750 aa)    
Predicted Functional Partners:
ACE2
Angiotensin-converting enzyme.
   
 
 0.977
IDE
Insulin degrading enzyme.
   
  
 0.963
PRCP
Prolylcarboxypeptidase.
   
 
 0.955
DPP4
Dipeptidyl peptidase 4; Belongs to the peptidase S9B family.
   
 
 0.954
MEP1A
Meprin A subunit.
     
 0.918
MEP1B
Meprin A subunit.
     
 0.915
XPNPEP2
X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family.
   
 
 0.914
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
      
 0.805
DIPK2A
Divergent protein kinase domain 2A.
   
    0.797
AGT
Angiotensinogen; Belongs to the serpin family.
    
 0.794
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.