STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
JAK2Tyrosine-protein kinase. (1131 aa)    
Predicted Functional Partners:
SOCS3
Suppressor of cytokine signaling 3.
   
 0.999
EPOR
Erythropoietin receptor; Receptor for erythropoietin.
   
 0.999
STAT3
Signal transducer and activator of transcription.
   
 0.999
IFNGR2
Interferon gamma receptor 2.
   
 0.999
PRLR
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
    
 0.998
SOCS1
Suppressor of cytokine signaling 1.
   
 0.998
STAT1
Signal transducer and activator of transcription.
   
 0.998
STAT5A
Signal transducer and activator of transcription.
   
 0.997
JAK1
Tyrosine-protein kinase.
   
0.995
STAT6
Signal transducer and activator of transcription.
   
 0.994
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.