SLC15A1 protein (Equus caballus) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

SLC15A1

Solute carrier family 15 member 1. (707 aa)

Predicted Functional Partners:

SULT1C3

0.798

SLC22A15

0.758

BLK

0.716

SLC9A3

0.706

ABCC2

0.677

WIPF1

0.603

DSG1

0.596

SLC13A3

0.583

NADK

0.576

FCRLA

0.568

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCC2	SLC15A1	ENSECAP00000018548	ENSECAP00000008210	ATP binding cassette subfamily C member 2.	Solute carrier family 15 member 1.	0.677
BLK	DSG1	ENSECAP00000015935	ENSECAP00000033241	Tyrosine-protein kinase.	Desmoglein 1.	0.715
BLK	FCRLA	ENSECAP00000015935	ENSECAP00000044905	Tyrosine-protein kinase.	Fc receptor like A.	0.741
BLK	SLC15A1	ENSECAP00000015935	ENSECAP00000008210	Tyrosine-protein kinase.	Solute carrier family 15 member 1.	0.716
BLK	SULT1C3	ENSECAP00000015935	ENSECAP00000018347	Tyrosine-protein kinase.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.907
BLK	WIPF1	ENSECAP00000015935	ENSECAP00000054426	Tyrosine-protein kinase.	WAS/WASL interacting protein family member 1.	0.739
DSG1	BLK	ENSECAP00000033241	ENSECAP00000015935	Desmoglein 1.	Tyrosine-protein kinase.	0.715
DSG1	SLC15A1	ENSECAP00000033241	ENSECAP00000008210	Desmoglein 1.	Solute carrier family 15 member 1.	0.596
DSG1	SULT1C3	ENSECAP00000033241	ENSECAP00000018347	Desmoglein 1.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.786
DSG1	WIPF1	ENSECAP00000033241	ENSECAP00000054426	Desmoglein 1.	WAS/WASL interacting protein family member 1.	0.584
FCRLA	BLK	ENSECAP00000044905	ENSECAP00000015935	Fc receptor like A.	Tyrosine-protein kinase.	0.741
FCRLA	SLC15A1	ENSECAP00000044905	ENSECAP00000008210	Fc receptor like A.	Solute carrier family 15 member 1.	0.568
FCRLA	SLC22A15	ENSECAP00000044905	ENSECAP00000017716	Fc receptor like A.	Solute carrier family 22 member 15.	0.674
NADK	SLC15A1	ENSECAP00000020523	ENSECAP00000008210	NAD kinase.	Solute carrier family 15 member 1.	0.576
SLC13A3	SLC15A1	ENSECAP00000008631	ENSECAP00000008210	Solute carrier family 13 member 3.	Solute carrier family 15 member 1.	0.583
SLC15A1	ABCC2	ENSECAP00000008210	ENSECAP00000018548	Solute carrier family 15 member 1.	ATP binding cassette subfamily C member 2.	0.677
SLC15A1	BLK	ENSECAP00000008210	ENSECAP00000015935	Solute carrier family 15 member 1.	Tyrosine-protein kinase.	0.716
SLC15A1	DSG1	ENSECAP00000008210	ENSECAP00000033241	Solute carrier family 15 member 1.	Desmoglein 1.	0.596
SLC15A1	FCRLA	ENSECAP00000008210	ENSECAP00000044905	Solute carrier family 15 member 1.	Fc receptor like A.	0.568
SLC15A1	NADK	ENSECAP00000008210	ENSECAP00000020523	Solute carrier family 15 member 1.	NAD kinase.	0.576

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006796

Phosphate-containing compound metabolic process

9 of 236

1.01

1.17

2.57e-07

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 327

0.86

0.88

3.63e-06

GO:1901566

Organonitrogen compound biosynthetic process

9 of 407

0.77

0.72

2.10e-05

GO:0006139

Nucleobase-containing compound metabolic process

9 of 537

0.65

0.55

0.00022

GO:0034641

Cellular nitrogen compound metabolic process

10 of 707

0.57

0.49

0.00014

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

8 of 9

2.37

6.45

1.76e-14

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 3

2.25

1.23

0.0050

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045259

Proton-transporting ATP synthase complex

8 of 9

2.37

6.71

3.72e-15

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 6

2.34

4.18

3.68e-09

GO:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

3 of 3

2.42

2.56

1.40e-05

GO:0005886

Plasma membrane

8 of 491

0.64

0.51

0.00095

GO:0005622

Intracellular anatomical structure

10 of 1040

0.41

0.33

0.0029

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:22479625

(2012) Comparative analysis of gene content evolution in phytoplasmas and mycoplasmas.

4 of 102

1.02

0.56

0.0355

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:249

ATP synthesis

8 of 8

2.42

6.65

1.05e-14

CL:84

Ribosome, and Ribonucleoside triphosphate biosynthetic process

10 of 91

1.46

2.77

5.39e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pth00190

Oxidative phosphorylation

9 of 19

2.1

6.04

8.55e-16

pth01100

Metabolic pathways

8 of 503

0.63

0.47

0.0041

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045259

Proton-transporting ATP synthase complex

8 of 10

2.33

6.39

1.27e-14

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 5

2.42

4.26

3.81e-09

GOCC:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

3 of 5

2.2

2.13

7.39e-05

GOCC:0032991

Protein-containing complex

9 of 435

0.74

0.67

6.39e-05

GOCC:0005622

Intracellular

10 of 995

0.43

0.34

0.0039

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0375

Hydrogen ion transport

8 of 8

2.42

6.87

3.09e-15

KW-0066

ATP synthesis

8 of 8

2.42

6.87

3.09e-15

KW-0139

CF(1)

5 of 5

2.42

4.29

3.15e-09

KW-0138

CF(0)

3 of 3

2.42

2.46

2.19e-05

KW-1003

Cell membrane

8 of 110

1.29

1.85

2.66e-08

(more ...)

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