STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRP3LDL receptor related protein 3. (769 aa)    
Predicted Functional Partners:
GGCX
Gamma-glutamyl carboxylase.
   
 
 0.638
APLP1
Amyloid beta precursor like protein 1.
    
 0.568
ITSN2
Intersectin 2.
    
 0.507
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
      
 0.463
FKRP
Fukutin related protein.
     
 0.462
CCNE1
Cyclin E1; Belongs to the cyclin family.
      
 0.457
LRCH1
Leucine rich repeats and calponin homology domain containing 1.
    
 0.457
RTN1
Reticulon.
   
  
 0.449
LRPAP1
LDL receptor related protein associated protein 1.
    
 0.444
SACM1L
SAC1 like phosphatidylinositide phosphatase.
    
 0.434
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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