STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGRP1RAS guanyl releasing protein 1. (797 aa)    
Predicted Functional Partners:
RAP1B
Ras-related protein Rap-1b-like protein.
    
 0.968
LOC100049912
Uncharacterized protein.
    
 0.964
KRAS
KRAS proto-oncogene, GTPase.
    
 0.957
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.952
HRAS
HRas proto-oncogene, GTPase.
    
 0.951
NRAS
NRAS proto-oncogene, GTPase.
    
 0.951
RASGRP2
RAS guanyl releasing protein 2.
  
 
0.916
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
     
0.915
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
     
0.915
RRAS
RAS related.
    
 0.807
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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