STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F7DPV9_HORSEUncharacterized protein. (145 aa)    
Predicted Functional Partners:
DCTN3
Dynactin subunit 3.
      
 0.901
IST1
IST1 factor associated with ESCRT-III.
  
  
 
0.901
VPS4A
Uncharacterized protein; Belongs to the AAA ATPase family.
   
 0.870
SPAST
Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]
    
 0.847
CHMP2A
Charged multivesicular body protein 2A.
    
 0.840
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
   
 0.768
CHMP3
Uncharacterized protein.
    
 0.753
VTA1
Vesicle trafficking 1.
   
 
 0.735
SPART
Spartin.
    
 
 0.731
CHMP4C
Charged multivesicular body protein 4C.
    
 0.730
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.