node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD4 | IFNG | ENSECAP00000007248 | ENSECAP00000030547 | CD4 molecule. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.971 |
CD4 | IL15 | ENSECAP00000007248 | ENSECAP00000025188 | CD4 molecule. | Interleukin; Belongs to the IL-15/IL-21 family. | 0.850 |
CD4 | IL2 | ENSECAP00000007248 | ENSECAP00000013353 | CD4 molecule. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.963 |
CD4 | IL7 | ENSECAP00000007248 | ENSECAP00000018195 | CD4 molecule. | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. | 0.858 |
CD4 | JAK1 | ENSECAP00000007248 | ENSECAP00000016857 | CD4 molecule. | Tyrosine-protein kinase. | 0.629 |
CD4 | JAK2 | ENSECAP00000007248 | ENSECAP00000008048 | CD4 molecule. | Tyrosine-protein kinase. | 0.578 |
CD4 | JAK3 | ENSECAP00000007248 | ENSECAP00000042461 | CD4 molecule. | Tyrosine-protein kinase. | 0.538 |
CD4 | LOC111769802 | ENSECAP00000007248 | ENSECAP00000008818 | CD4 molecule. | Interleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP) (By similarity); Belongs to the type I cytokine receptor family. Type 4 subfamily. | 0.889 |
CD4 | TSLP | ENSECAP00000007248 | ENSECAP00000027409 | CD4 molecule. | Thymic stromal lymphopoetin. | 0.652 |
ENSECAP00000039540 | JAK2 | ENSECAP00000039540 | ENSECAP00000008048 | Fibronectin type-III domain-containing protein. | Tyrosine-protein kinase. | 0.470 |
ENSECAP00000039540 | LOC111769802 | ENSECAP00000039540 | ENSECAP00000008818 | Fibronectin type-III domain-containing protein. | Interleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP) (By similarity); Belongs to the type I cytokine receptor family. Type 4 subfamily. | 0.942 |
ENSECAP00000039540 | TSLP | ENSECAP00000039540 | ENSECAP00000027409 | Fibronectin type-III domain-containing protein. | Thymic stromal lymphopoetin. | 0.929 |
IFNG | CD4 | ENSECAP00000030547 | ENSECAP00000007248 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | CD4 molecule. | 0.971 |
IFNG | IL15 | ENSECAP00000030547 | ENSECAP00000025188 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Interleukin; Belongs to the IL-15/IL-21 family. | 0.937 |
IFNG | IL2 | ENSECAP00000030547 | ENSECAP00000013353 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. | 0.976 |
IFNG | IL7 | ENSECAP00000030547 | ENSECAP00000018195 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. | 0.884 |
IFNG | JAK1 | ENSECAP00000030547 | ENSECAP00000016857 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Tyrosine-protein kinase. | 0.991 |
IFNG | JAK2 | ENSECAP00000030547 | ENSECAP00000008048 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Tyrosine-protein kinase. | 0.989 |
IFNG | JAK3 | ENSECAP00000030547 | ENSECAP00000042461 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Tyrosine-protein kinase. | 0.676 |
IFNG | LOC111769802 | ENSECAP00000030547 | ENSECAP00000008818 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | Interleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP) (By similarity); Belongs to the type I cytokine receptor family. Type 4 subfamily. | 0.881 |