STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TP53INP2Tumor protein p53 inducible nuclear protein 2. (221 aa)    
Predicted Functional Partners:
GABARAPL2
Gamma-aminobutyric acid receptor-associate protein-like 2-like protein.
    
 0.930
GABARAP
GABA type A receptor-associated protein.
    
 0.918
NUPR2
Nuclear protein 2, transcriptional regulator.
      
 0.884
DRAM1
DNA damage regulated autophagy modulator 1.
      
 0.692
NUPR1
Nuclear protein 1, transcriptional regulator.
      
 0.666
VAMP8
Vesicle associated membrane protein 8.
      
 0.589
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
    
 0.565
CDC5L
Cell division cycle 5 like.
   
  
 0.507
NMT1
Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family.
      
 0.482
CAMKK1
Calcium/calmodulin dependent protein kinase kinase 1.
   
  
 0.479
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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