STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)    
Predicted Functional Partners:
ZG16
Zymogen granule protein 16.
      
 0.772
SPDEF
SAM pointed domain containing ETS transcription factor.
   
  
 0.637
ZAR1L
Zygote arrest 1 like.
      
 0.629
TFF3
Trefoil factor 3.
   
  
 0.576
GCNT4
Glucosaminyl (N-acetyl) transferase 4.
      
 0.546
KLK1
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
      
 0.530
FCGBP
Uncharacterized protein.
    
 
 0.529
FXYD3
FXYD domain-containing ion transport regulator; Belongs to the FXYD family.
   
  
 0.518
CLCA1
Calcium-activated chloride channel regulator 1; May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC (By similarity).
   
 
 0.507
LYPD3
LY6/PLAUR domain containing 3.
    
 
 0.500
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (18%) [HD]