IRS4 protein (Equus caballus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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Score

IRS4

Insulin receptor substrate 4. (1355 aa)

Predicted Functional Partners:

IGF1R

0.983

INSR

0.967

INS

0.959

JAK2

0.955

PIK3CG

0.951

KL

0.925

SOCS1

0.923

SOCS2

0.923

MTOR

0.923

PTPN1

0.920

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGF1R	INS	ENSECAP00000019400	ENSECAP00000022114	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.999
IGF1R	INSR	ENSECAP00000019400	ENSECAP00000008032	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.984
IGF1R	IRS4	ENSECAP00000019400	ENSECAP00000009452	Tyrosine-protein kinase receptor.	Insulin receptor substrate 4.	0.983
IGF1R	JAK2	ENSECAP00000019400	ENSECAP00000008048	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase.	0.954
IGF1R	KL	ENSECAP00000019400	ENSECAP00000006226	Tyrosine-protein kinase receptor.	Klotho.	0.948
IGF1R	MTOR	ENSECAP00000019400	ENSECAP00000049618	Tyrosine-protein kinase receptor.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.442
IGF1R	PTPN1	ENSECAP00000019400	ENSECAP00000023440	Tyrosine-protein kinase receptor.	Protein tyrosine phosphatase non-receptor type 1.	0.924
IGF1R	SOCS1	ENSECAP00000019400	ENSECAP00000022763	Tyrosine-protein kinase receptor.	Suppressor of cytokine signaling 1.	0.444
INS	IGF1R	ENSECAP00000022114	ENSECAP00000019400	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.999
INS	INSR	ENSECAP00000022114	ENSECAP00000008032	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.999
INS	IRS4	ENSECAP00000022114	ENSECAP00000009452	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin receptor substrate 4.	0.959
INS	JAK2	ENSECAP00000022114	ENSECAP00000008048	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase.	0.667
INS	KL	ENSECAP00000022114	ENSECAP00000006226	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Klotho.	0.425
INS	MTOR	ENSECAP00000022114	ENSECAP00000049618	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.676
INS	PTPN1	ENSECAP00000022114	ENSECAP00000023440	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Protein tyrosine phosphatase non-receptor type 1.	0.436
INSR	IGF1R	ENSECAP00000008032	ENSECAP00000019400	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.984
INSR	INS	ENSECAP00000008032	ENSECAP00000022114	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.999
INSR	IRS4	ENSECAP00000008032	ENSECAP00000009452	Tyrosine-protein kinase receptor.	Insulin receptor substrate 4.	0.967
INSR	KL	ENSECAP00000008032	ENSECAP00000006226	Tyrosine-protein kinase receptor.	Klotho.	0.916
INSR	PTPN1	ENSECAP00000008032	ENSECAP00000023440	Tyrosine-protein kinase receptor.	Protein tyrosine phosphatase non-receptor type 1.	0.999