node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ESR1 | FKBP4 | ENSECAP00000020141 | ENSECAP00000018238 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Peptidylprolyl isomerase. | 0.624 |
ESR1 | LOC100052122 | ENSECAP00000020141 | ENSECAP00000031451 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Uncharacterized protein. | 0.644 |
ESR1 | NCOA1 | ENSECAP00000020141 | ENSECAP00000038479 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Nuclear receptor coactivator. | 0.998 |
ESR1 | NCOA3 | ENSECAP00000020141 | ENSECAP00000044340 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Nuclear receptor coactivator. | 0.998 |
ESR1 | PGR | ENSECAP00000020141 | ENSECAP00000009675 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Progesterone receptor. | 0.977 |
ESR1 | PIK3CA | ENSECAP00000020141 | ENSECAP00000013092 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.849 |
ESR1 | PIK3R1 | ENSECAP00000020141 | ENSECAP00000017836 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Phosphoinositide-3-kinase regulatory subunit 1. | 0.788 |
ESR1 | PIK3R2 | ENSECAP00000020141 | ENSECAP00000023307 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Uncharacterized protein. | 0.644 |
ESR1 | PRKACA | ENSECAP00000020141 | ENSECAP00000030791 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. | 0.953 |
ESR1 | PRKACB | ENSECAP00000020141 | ENSECAP00000039657 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.952 |
FKBP4 | ESR1 | ENSECAP00000018238 | ENSECAP00000020141 | Peptidylprolyl isomerase. | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | 0.624 |
FKBP4 | PGR | ENSECAP00000018238 | ENSECAP00000009675 | Peptidylprolyl isomerase. | Progesterone receptor. | 0.942 |
LOC100052122 | ESR1 | ENSECAP00000031451 | ENSECAP00000020141 | Uncharacterized protein. | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | 0.644 |
LOC100052122 | PGR | ENSECAP00000031451 | ENSECAP00000009675 | Uncharacterized protein. | Progesterone receptor. | 0.920 |
LOC100052122 | PIK3CA | ENSECAP00000031451 | ENSECAP00000013092 | Uncharacterized protein. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.998 |
LOC100052122 | PIK3R1 | ENSECAP00000031451 | ENSECAP00000017836 | Uncharacterized protein. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.989 |
LOC100052122 | PIK3R2 | ENSECAP00000031451 | ENSECAP00000023307 | Uncharacterized protein. | Uncharacterized protein. | 0.980 |
NCOA1 | ESR1 | ENSECAP00000038479 | ENSECAP00000020141 | Nuclear receptor coactivator. | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | 0.998 |
NCOA1 | NCOA3 | ENSECAP00000038479 | ENSECAP00000044340 | Nuclear receptor coactivator. | Nuclear receptor coactivator. | 0.979 |
NCOA1 | PGR | ENSECAP00000038479 | ENSECAP00000009675 | Nuclear receptor coactivator. | Progesterone receptor. | 0.945 |