TBC1D19 protein (Equus caballus) - STRING interaction network

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Predicted Interactions

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Score

TBC1D19

TBC1 domain family member 19. (526 aa)

Predicted Functional Partners:

TBC1D14

0.831

TBC1D10C

0.827

TBC1D21

0.827

TBC1D13

0.752

TBC1D17

0.722

TBC1D2

0.719

RNF8

0.705

TBC1D10B

0.703

TBC1D10A

0.701

TBC1D7

0.698

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RNF8	TBC1D10A	ENSECAP00000052860	ENSECAP00000016302	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	TBC1 domain family member 10A.	0.837
RNF8	TBC1D10B	ENSECAP00000052860	ENSECAP00000020453	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	TBC1 domain family member 10B.	0.826
RNF8	TBC1D10C	ENSECAP00000052860	ENSECAP00000009872	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	TBC1 domain family member 10C.	0.827
RNF8	TBC1D13	ENSECAP00000052860	ENSECAP00000005935	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	TBC1 domain family member 13.	0.413
RNF8	TBC1D19	ENSECAP00000052860	ENSECAP00000009762	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	TBC1 domain family member 19.	0.705
RNF8	TBC1D21	ENSECAP00000052860	ENSECAP00000022491	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	TBC1 domain family member 21.	0.828
RNF8	TBC1D7	ENSECAP00000052860	ENSECAP00000014779	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	TBC1 domain family member 7.	0.671
TBC1D10A	RNF8	ENSECAP00000016302	ENSECAP00000052860	TBC1 domain family member 10A.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.837
TBC1D10A	TBC1D13	ENSECAP00000016302	ENSECAP00000005935	TBC1 domain family member 10A.	TBC1 domain family member 13.	0.567
TBC1D10A	TBC1D14	ENSECAP00000016302	ENSECAP00000046986	TBC1 domain family member 10A.	TBC1 domain family member 14.	0.478
TBC1D10A	TBC1D17	ENSECAP00000016302	ENSECAP00000001564	TBC1 domain family member 10A.	TBC1 domain family member 17.	0.489
TBC1D10A	TBC1D19	ENSECAP00000016302	ENSECAP00000009762	TBC1 domain family member 10A.	TBC1 domain family member 19.	0.701
TBC1D10A	TBC1D21	ENSECAP00000016302	ENSECAP00000022491	TBC1 domain family member 10A.	TBC1 domain family member 21.	0.821
TBC1D10A	TBC1D7	ENSECAP00000016302	ENSECAP00000014779	TBC1 domain family member 10A.	TBC1 domain family member 7.	0.647
TBC1D10B	RNF8	ENSECAP00000020453	ENSECAP00000052860	TBC1 domain family member 10B.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.826
TBC1D10B	TBC1D13	ENSECAP00000020453	ENSECAP00000005935	TBC1 domain family member 10B.	TBC1 domain family member 13.	0.768
TBC1D10B	TBC1D14	ENSECAP00000020453	ENSECAP00000046986	TBC1 domain family member 10B.	TBC1 domain family member 14.	0.478
TBC1D10B	TBC1D19	ENSECAP00000020453	ENSECAP00000009762	TBC1 domain family member 10B.	TBC1 domain family member 19.	0.703
TBC1D10B	TBC1D21	ENSECAP00000020453	ENSECAP00000022491	TBC1 domain family member 10B.	TBC1 domain family member 21.	0.788
TBC1D10B	TBC1D7	ENSECAP00000020453	ENSECAP00000014779	TBC1 domain family member 10B.	TBC1 domain family member 7.	0.664